1. Structural basis of Ca2+-dependent activation and lipid transport by a TMEM16 scramblase. Falzone ME, Rheinberger J, Lee BC, Peyear T, Sasset L, Raczkowski AM, Eng ET, Di Lorenzo A, Andersen OS, Nimigean CM, Accardi A. Elife. 2019 Jan 16;8. pii: e43229. doi: 10.7554/eLife.43229.

2. Gating mechanism of the extracellular entry to the lipid pathway in a TMEM16 scramblase. Lee BC, Khelashvili G, Falzone M, Menon AK, Weinstein H, Accardi A. Nat Commun. 2018 Aug 14;9(1):3251. doi: 10.1038/s41467-018-05724-1.

3. Out-of-the-groove transport of lipids by TMEM16 and GPCR scramblases. Malvezzi M, Andra KK, Pandey K, Lee BC, Falzone ME, Brown A, Iqbal R, Menon AK, Accardi A. Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7033-E7042. doi: 10.1073/pnas.1806721115. Epub 2018 Jun 20.

4. Known structures and unknown mechanisms of TMEM16 scramblases and channels. Falzone ME, Malvezzi M, Lee BC, Accardi A. J Gen Physiol. 2018 Jul 2;150(7):933-947. doi: 10.1085/jgp.201711957. Epub 2018 Jun 18. Review.

5. Probing the conformation of a conserved glutamic acid within the Cl- pathway of a CLC H+/Cl- exchanger. Vien M, Basilio D, Leisle L, Accardi A. J Gen Physiol. 2017 Apr 3;149(4):523-529. doi: 10.1085/jgp.201611682. Epub 2017 Feb 28.

6. The nhTMEM16 Scramblase Is Also a Nonselective Ion Channel. Lee BC, Menon AK, Accardi A. Biophys J. 2016 Nov 1;111(9):1919-1924. doi: 10.1016/j.bpj.2016.09.032.

7. CELL SIGNALING. Lipids link ion channels and cancer. Accardi A. Science. 2015 Aug 21;349(6250):789-90. doi: 10.1126/science.aad0874.

8. Structure and gating of CLC channels and exchangers. Accardi A. J Physiol. 2015 Sep 15;593(18):4129-38. doi: 10.1113/JP270575. Epub 2015 Jul 28. Review.

9. A Proteoliposome-Based Efflux Assay to Determine Single-molecule Properties of Cl- Channels and Transporters. Basilio D, Accardi A. J Vis Exp. 2015 Apr 20;(98). doi: 10.3791/52369.

10. Unveiling the secret lives of glutamate transporters: VGLUTs engage in multiple transport modes. Accardi A. Neuron. 2014 Dec 17;84(6):1110-2. doi: 10.1016/j.neuron.2014.12.008.

11. TMEM16 proteins: unknown structure and confusing functions. Picollo A, Malvezzi M, Accardi A. J Mol Biol. 2015 Jan 16;427(1):94-105. doi: 10.1016/j.jmb.2014.09.028. Epub 2014 Oct 17. Review.

12. Nucleotide binding triggers a conformational change of the CBS module of the magnesium transporter CNNM2 from a twisted towards a flat structure. Corral-Rodríguez MÁ, Stuiver M, Abascal-Palacios G, Diercks T, Oyenarte I, Ereño-Orbea J, de Opakua AI, Blanco FJ, Encinar JA, Spiwok V, Terashima H, Accardi A, Müller D, Martínez-Cruz LA. Biochem J. 2014 Nov 15;464(1):23-34. doi: 10.1042/BJ20140409.

13. Conformational changes required for H(+)/Cl(-) exchange mediated by a CLC transporter. Basilio D, Noack K, Picollo A, Accardi A. Nat Struct Mol Biol. 2014 May;21(5):456-63. doi: 10.1038/nsmb.2814. Epub 2014 Apr 20.

14. Purified TMEM16A is sufficient to form Ca2+-activated Cl- channels. Terashima H, Picollo A, Accardi A. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19354-9. doi: 10.1073/pnas.1312014110. Epub 2013 Oct 28.

15. Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel. Malvezzi M, Chalat M, Janjusevic R, Picollo A, Terashima H, Menon AK, Accardi A. Nat Commun. 2013;4:2367. doi: 10.1038/ncomms3367.

16. Synergistic substrate binding determines the stoichiometry of transport of a prokaryotic H(+)/Cl(-) exchanger. Picollo A, Xu Y, Johner N, Bernèche S, Accardi A. Nat Struct Mol Biol. 2012 Apr 8;19(5):525-31, S1. doi: 10.1038/nsmb.2277.

17. PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons. Ying SW, Tibbs GR, Picollo A, Abbas SY, Sanford RL, Accardi A, Hofmann F, Ludwig A, Goldstein PA. J Neurosci. 2011 Jul 13;31(28):10412-23. doi: 10.1523/JNEUROSCI.0021-11.2011.

18. A dystroglycan mutation associated with limb-girdle muscular dystrophy. Hara Y, Balci-Hayta B, Yoshida-Moriguchi T, Kanagawa M, Beltrán-Valero de Bernabé D, Gündeşli H, Willer T, Satz JS, Crawford RW, Burden SJ, Kunz S, Oldstone MB, Accardi A, Talim B, Muntoni F, Topaloğlu H, Dinçer P, Campbell KP. N Engl J Med. 2011 Mar 10;364(10):939-46. doi: 10.1056/NEJMoa1006939.

19. Proton block of the CLC-5 Cl-/H+ exchanger. Picollo A, Malvezzi M, Accardi A. J Gen Physiol. 2010 Jun;135(6):653-9. doi: 10.1085/jgp.201010428.

20. CLC channels and transporters: proteins with borderline personalities. Accardi A, Picollo A. Biochim Biophys Acta. 2010 Aug;1798(8):1457-64. doi: 10.1016/j.bbamem.2010.02.022. Epub 2010 Feb 24. Review.

21. Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters. Picollo A, Malvezzi M, Houtman JC, Accardi A. Nat Struct Mol Biol. 2009 Dec;16(12):1294-301. doi: 10.1038/nsmb.1704. Epub 2009 Nov 8.

22. Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger. Jayaram H, Accardi A, Wu F, Williams C, Miller C. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11194-9. doi: 10.1073/pnas.0804503105. Epub 2008 Aug 4.

23. To ATP or not to ATP: this is the question. Accardi A. J Gen Physiol. 2008 Feb;131(2):105-8. doi: 10.1085/jgp.200709953. No abstract available.